PTQ Faecal Incontinence Implant

Injectable Soft-tissue Bulking Agent

PTQ is implanted in the Internal Anal Sphincter (IAS) to treat passive faecal incontinence due to a weak or disrupted internal anal sphincter. The procedure is minimally invasive and technically simple (Ref 1). It can be performed under local anaesthesia in an outpatient setting.

Proven Performance

  • Up to 95% of patients show a significant improvement in incontinence scores 2,3
  • Provides sustainable improvement for 12-24 months 2-10
  • Improves patient quality of life 2-4, 7, 11
  • Reinjection is effective 5
  • Helps improve anal asymmetry index which may be linked to increased maximum resting anal canal pressures 2

PTQ-Faecal-Incontinence-Implant-improvement

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References
1. PTQ – 2007 – Evaluation of the use of PTQ implants for the treatment of incontinent patients due to internal anal sphincter dysfunction
2.
Oliveira, L.C.C., Jorge, J.M.N., Yussuf, S. Habr-Gama, A., Kiss, D., & Cecconello, I. (2009). Anal incontinence improvement after silicone injection may be related to restoration of sphincter asymmetry. Surgical Innovation, 16(2), 155-161.
3. Bartlett,L. & Ho, Y.H.(2009). PTQTM anal implants for the treatment of faecal incontinence. British Journal of Surgery, 96, 1468-1475.
4. Tjandra, J.J., Chan, M.K.Y., & Yeh, H.C.H. (2009). Injectable silicone biomaterial (PTQ™) is more effective than carbon-coated beads (Durasphere®) in treating passive faecal incontinence – A randomised trial. Colorectal Dis., 11, 382-389.
5. Tjandra, J.J., Lim, J.F., Hiscock, R., & Rajendra, P. (2004). Injectable silicone biomaterial for fecal incontinence caused by internal anal sphincter dysfunction is effective. Dis Colon Rectum, 47, 2138-2146.
6. van der Hagen, S.J., van Gemert, W.G., & Baeten, C.G. (2007). PTQ™ Implants in the treatment of faecal soiling. Br J. Surgery, 94, 222-223.
7. de la Portilla, F., Fernández, A., León, E., Rada, R., Cisneros, N., Maldonado, V.H., Vega, J., & Espinoda, E. (2008). Evaluation of the use of PTQ™ implants for the treatment of incontinent patients due to internal anal sphincter dysfunction. Colorectal Dis, 10, 89-94.
8. Kenefick, N.J., Vaizey, C.J., Malouf, A.J., Norton, C.S., Marshall, M., & Kamm, M.A. (2002). Injectable silicone biomaterial for faecal incontinence due to internal anal sphincter dysfunction. Gut, 51, 225-228. 77(Suppl 1), A16.
9. Gaj, F., Trecca, A., & Crispino, P. (2007). “[Efficacy of PTQ agent in the treatment of faecal incontinence].” Chir Ital, 59(3), 355-359.
10. Tjandra, J.J., Tan, J., Lim, F., & Murray-Green, C. (2006). Long-term results of injectable silicone biomaterial for passive fecal incontinence – A randomized trial. Dis Colon Rectum, 49(5), 730-731.
11. Bach, S., Lindsey, I., George, B., Cunningham, C., & McC. Mortensen, N.J. (2004). Implantable silicone for passive fecal incontinence secondary to internal anal sphincter deficiency. Poster ASCRP, Dallas, USA.

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