LiftUp serves as an injection agent for endoscopic resection techniques such as ESD, EMR and POEM. It gels thermoreversibly at body temperature and forms a stable and long-lasting cushion in the submucosa. It optimally supplements the resection techniques EMR+ and ESD+.
LiftUp creates a submucosal gel cushion at body temperature due to its thermoreversible properties. It is a new injection solution for safe and easy¹ endoscopic resection, such as polypectomy, EMR and ESD. The pronounced safety cushion lasts even after mucosa incision.² Tissue layers and structures are well separated and exposed, thereby facilitating the resection procedure. The long-lasting lifting makes re-injection less necessary and saves time.³ Each vial contains 20 ml of LiftUp® pre-mixed with methylene blue and is ready-to-use.
1. Wedi, E., Ho, C.-N., Conrad, G., Weiland, T., Freidinger, S., Wehrmann, M., Meining, A., Ellenrieder, V., Gottwald, T., Schurr, MO., Hochberger, J. (2019). Preclinical evaluation of a novel thermally sensitive co-polymer (LiftUp) for endoscopic resection. Minim Invasive Ther Allied Technol, 28(5), 277–284. doi: 10.1080/13645706.2018.1535440
2. Wedi, E., Koehler, P., Hochberger, J., Maiss, J., Milenovic, S., Gromski, M., Ho, C.-N., Gabor, C., Baulain, U., Ellenrieder, V., Jung, C. (2019). Endoscopic submucosal dissection with a novel high viscosity injection solution (LiftUp) in an ex vivo model: a prospective randomized study. Endosc Int Open, 07(05). doi: 10.1055/a-0874-1844
3. Meier, B., Wannhoff, A., Klinger, C., & Caca, K. (2019). Novel technique for endoscopic en bloc resection (EMR+) – Evaluation in a porcine model. World J Gastroenterol, 25(28), 3764–3774. doi: 10.3748/wjg.v25.i28.3764