The Biodesign Otologic Repair Graft is an implantable biomaterial that aids in the natural healing process in otologic procedures. It is indicated for use in myringoplasty and tympanoplasty procedures.
Biodesign grafts encompass the biological properties of porcine small intestinal submucosa (SIS). SIS provides a natural scaffold that allows the body to restore itself through the complex natural process of tissue remodelling. Tissue remodelling involves the recruitment of cells, the renewal of tissue composition, and the reinforcement of structural tissue architecture.2 As the body heals, SIS is gradually remodelled and integrated into the body, leaving behind organised tissue that provides long-term strength.1,3,4
The Biodesign Otologic Repair Graft completely remodels into natural host tissue, resulting in closure rates ranging from 83%–100% across published literature.1,5,6
Biodesign material is easy to manipulate, allowing for improved surgical precision during graft placement.5
The Biodesign Otologic Repair Graft reduces the need to harvest autologous tissue, significantly decreasing intraoperative time.6
1. D’Eredità R. Porcine small intestinal submucosa (SIS) myringoplasty in children: arandomized controlled study. Int J Pediatr Otorhinolaryngol. 2015;79(7):1085-1089.
2. Franklin ME Jr, Trevino JM, Portillo G, Vela I, Glass JL, Gonzalez JJ. The use of porcine small intestinal submucosa as a prosthetic material for laparoscopic hernia repair in infected and potentially contaminated field: Long-term follow-up. Surg Endosc. 2008;22(9):1941-1946.
3. Stelly M, Stelly TC. Histology of CorMatrix bioscaffold 5 years after pericardial closure. Ann Thorac Surg. 2013;96(5):e127-e129.
4. Badylak S, Kokini K, Tullius B, Whitson B. Strength over time of a resorbable bioscaffold for body wall repair in a dog model. J Surg Res. 2001;99(2):282-287.
5. James AL. Endoscope or microscope-guided pediatric tympanoplasty? Comparison of grafting technique and outcome. Laryngoscope. 2017;127(11):2659-2664.
6. De Zinis LO, Berlucchi M, Nassif N. Double-handed endoscopic myringoplasty with a holding system in children: preliminary observations. Int J Pediatr Otorhinolaryngol. 2017; 96:127-130.