PureRegen is an injectable dressing gel used after FESS Surgery to improve mucous healing. PureRegen is formulated from crosslinked hyaluronic acid, purely from bacterial fermentation and contains no animal components.

Controlled Degradation Profile

The PureRegen degradation profile matches the critical repair period, especially the inflammatory processes after surgery, providing an effective barrier between the mucosal surfaces to prevent adhesion. PureRegen dissolves in 14 days, eliminating the need for pailful packing removal and secondary damage to fresh mucous. (1,2)



  • Promotes functional healing: Stops minor bleeding and facilitates remucosalisation.
  • Expands after plantation: Conforms to nasal cavity leaving no dead space.
  • Degrades in 2 weeks: Eliminates painful removal and avoids secondary damage to regenerated mucous.
  • Biocompatible: Non-animal components, no xenogetic material, no toxic residual.
  • Ready to use in syringe: With mouldable cannula. No need to pre-mix.
  • Stored at room temperature.


Proven Results

Prospective, randomised, controlled multiple centre clinical studies (level 1) in China and the USA demonstrated that PureRegen Gel resulted in less adhesion, better remucosalisation, and reduced edema and crust than the control group. (3,4,5)

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Reference Material


  • Watelet JB, et al: Wound Healing of the Nasal and Paranasal Mucosa: A Review. American Journal of Rhinology and Allergy 16:77-84, 2002.
  • Pajic-Penavic I.: Endoscopic Monitoring of Postoperative Sinonasal Mucosa Wounds Healing. Advances in Endoscopic Surgery, Prof. Cornel Lancu (Ed.), InTech. 21:419-436, 2001.
  • Shi R., et al. The Clinical Outcomes of New Hyaluroan Nasal Dressing: A Prospective Randomised, Controlled Study. American Journal of Rhinology and Allergy 27:71-76, 2013.
  • Matheny KM, et.al. Self-crosslinked hyaluronic acid hydrogel in ethmoidectomy: A Randomised, controlled trial. American Journal of Rhinology and Allergy 28:508-513, 2014.
  • Preventing Adhesion and Keeping the ostia open after Functional Endoscopic Frontal Sinus Surgery by a Novel Crosslinked Hyaluronan Gel: Internal Data. Manuscript 2015.